Guidance on wastewater and solid waste management for manufacturing of antibiotics

United Nations 1 year ago

Control of pollution from antibiotic manufacturing is a key part of safeguarding the longevity of antibiotics for all. Pollution contributes to antibiotic resistance and potentially undermines the effectiveness of medicines. High levels of antibiotics in water bodies downstream of manufacturing sites have been widely documented. Currently, antibiotic pollution from manufacturing is largely unregulated and quality assurance criteria typically do not address environmental emissions. This guidance has been called for by a myriad of international bodies, strategies and reports.  Its purpose is to provide an independent scientific basis for inclusion of targets in binding instruments to prevent the emergence and spread of antibiotic resistance.The target audiences are: regulatory bodies; procurers of antibiotics; entities responsible for generic substitution schemes and reimbursement decisions; third-party audit and inspection bodies; industrial actors and their collective organizations and initiatives; investors; and waste and wastewater management services. This guidance also includes best practices for risk management, including internal and external audit and public transparency. Crucially, this guidance includes progressive implementation, and stepwise improvement when needed recognizing the need to protect and strengthen the global supply, and to ensure appropriate, affordable and equitable access to quality-assured antibiotics.  Read the press release New global guidance aims to curb antibiotic pollution from manufacturing Also available Frequently asked questions Background document: Evidence synthesis for deriving PNECs for resistance selection
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layersDaily Sustainability Digest

Published about 3 hours ago



AI-driven innovation is reshaping sustainable construction, as demonstrated by Greyparrot’s Analyser being named on TIME’s Best Inventions of 2025 list. The technology’s precision in identifying recyclable materials reinforces circular economy in construction principles and strengthens whole life carbon assessment practices by improving data capture on waste flows. This form of circular construction strategy supports resource efficiency in construction and encourages greater adoption of eco-design for buildings, reducing the embodied carbon in materials and promoting a measurable approach to the carbon footprint of construction. By integrating artificial intelligence into sorting systems, the industry is taking a critical step toward decarbonising the built environment through technology-led environmental sustainability in construction.

Recognising that machinery alone cannot achieve sustainability goals, the UK construction sector is prioritising human capital to meet the demands of net zero whole life carbon objectives. A coordinated drive to develop new green skills underscores the importance of life cycle thinking in construction and low carbon design expertise. Building professionals are being urged to strengthen their competence in sustainable building practices and whole life carbon management, ensuring future workforce capability in sustainable building design and renewable building materials. These efforts are vital for maintaining BREEAM and BREEAM v7 certification standards which continue to define quality benchmarks for low carbon building performance.

The European Union’s compromise on its Corporate Sustainability Reporting Directive (CSRD) and Corporate Sustainability Due Diligence Directive (CSDDD) is poised to reshape how construction firms disclose their environmental impacts. By applying due diligence primarily to large corporations, the policy risks excluding smaller firms from conducting full whole life carbon and lifecycle assessment reporting. Such omissions could distort visibility into total embodied carbon across supply chains, reducing transparency in life cycle cost evaluation. Broader inclusion would help achieve carbon footprint reduction across all tiers of the built environment and encourage greater adoption of sustainable material specification consistent with the circular economy.

Global scrutiny of sustainable architecture and construction is intensifying in the run-up to COP30, drawing political figures and sustainability advocates alike. Prince William’s planned attendance symbolises renewed commitment to net zero carbon buildings and carbon neutral construction policy, setting a high bar for environmental sustainability in construction targets. These global gatherings amplify pressure to deliver energy-efficient buildings and low carbon construction materials backed by environmental product declarations (EPDs). Governments and construction enterprises alike are expected to demonstrate measurable reductions in the carbon footprint of construction aligned with whole life carbon and embodied carbon standards.

Regulators in Wales have reinforced the importance of compliance as a foundation for sustainable construction. A significant fine imposed on a waste operator underscores how enforcement directly supports cleaner practices and enhances building lifecycle performance. Tackling illegal dumping not only prevents environmental degradation but also sustains the circular economy by protecting legitimate recycling pathways crucial for low-impact construction. Integrity in waste management underpins the success of sustainable design and ensures that resource efficiency in construction continues to strengthen green infrastructure. The ongoing shift toward environmentally responsible building demonstrates how strong governance, technical innovation, and skilled workforces can combine to reduce embodied carbon and ensure sustainability remains at the core of the construction industry.

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