Guidance on wastewater and solid waste management for manufacturing of antibiotics

United Nations 1 year ago

Control of pollution from antibiotic manufacturing is a key part of safeguarding the longevity of antibiotics for all. Pollution contributes to antibiotic resistance and potentially undermines the effectiveness of medicines. High levels of antibiotics in water bodies downstream of manufacturing sites have been widely documented. Currently, antibiotic pollution from manufacturing is largely unregulated and quality assurance criteria typically do not address environmental emissions. This guidance has been called for by a myriad of international bodies, strategies and reports.  Its purpose is to provide an independent scientific basis for inclusion of targets in binding instruments to prevent the emergence and spread of antibiotic resistance.The target audiences are: regulatory bodies; procurers of antibiotics; entities responsible for generic substitution schemes and reimbursement decisions; third-party audit and inspection bodies; industrial actors and their collective organizations and initiatives; investors; and waste and wastewater management services. This guidance also includes best practices for risk management, including internal and external audit and public transparency. Crucially, this guidance includes progressive implementation, and stepwise improvement when needed recognizing the need to protect and strengthen the global supply, and to ensure appropriate, affordable and equitable access to quality-assured antibiotics.  Read the press release New global guidance aims to curb antibiotic pollution from manufacturing Also available Frequently asked questions Background document: Evidence synthesis for deriving PNECs for resistance selection
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layersDaily Sustainability Digest

Published about 10 hours ago



The UK Government’s decision to triple domestic heat pump manufacturing funding to £90 million marks a significant step toward advancing net zero carbon buildings and sustainable construction. The investment, part of the Heat Pump Investment Accelerator Competition, supports a shift from fossil-fuel heating systems toward low carbon design alternatives. This strategy strengthens the UK’s capacity to measure and manage embodied carbon and whole life carbon across the built environment, setting a pathway for a new generation of energy-efficient buildings aligned with a circular economy in construction.

The funding increase is expected to boost supply chains for low embodied carbon materials, encouraging manufacturers to undertake whole life carbon assessment and lifecycle assessment processes when scaling production. By integrating life cycle cost considerations into both product development and procurement, construction firms can enhance environmental sustainability in construction and drive improvements in sustainable building practices that are measurable, verifiable, and fully compliant with BREEAM and BREEAM v7 certification frameworks.

Heat pumps are being positioned as a cornerstone of low carbon building performance, essential to reducing the carbon footprint of construction projects while improving renewable energy use in the housing sector. This transition links closely to sustainable building design and eco-design for buildings, where life cycle thinking in construction ensures long-term energy efficiency, resource efficiency in construction, and end-of-life reuse in construction. It forms part of a broader shift toward carbon neutral construction that aligns industry performance with national climate targets under the Clean Heat Mechanism.

The Government’s emphasis on green infrastructure and off-grid electric vehicle charging further supports sustainable urban development and decarbonising the built environment. Investment in renewable building materials and green building products underpins a new generation of low carbon construction materials built for the circular economy. These measures encourage stakeholders to consider embodied carbon in materials and carbon footprint reduction strategies, setting new benchmarks for sustainable design and environmental product declarations (EPDs).

Grassroots initiatives like the Dorset COP showcase how sustainable building practices can emerge from local engagement. By connecting policy ambition with practical delivery, such forums demonstrate the role of community-led sustainable architecture and eco-friendly construction in achieving net zero whole life carbon goals. This balanced approach to sustainable construction links technology, funding, and local action, forming the structural backbone of a low-impact construction future. Through collaboration and evidence-based standards, the UK’s construction sector continues to lay the foundations for a built environment defined by resilience, circular construction strategies, and enduring environmental stewardship.

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Whole Life Carbon is a platform for the entire construction industry—both in the UK and internationally. We track the latest publications, debates, and events related to whole life guidance and sustainability. If you have any enquiries or opinions to share, please do get in touch.